Chromatography Techniques and Spectrometry

Ion-Mobility Spectrometry-Mass Spectrometry (IMS-MS)

Ion-Mobility Separation-Mass Spectrometry is an another term of Ion-Mobility Spectrometry-Mass Spectrometry (IMS-MS), is an analytical technique on a millisecond timescale separates gas phase ions using ion-mobility spectrometry and on a microsecond timescale uses mass spectrometry to identify components in a sample.

The phenomenon of ion mobility (IM) was first observed in the early 20th Century and harnessed later in ion mobility spectrometry (IMS) based on the movement/transport of charged particles under the influence of an electric field. This theory together with contributions from computational chemistry and gas-phase ion chemistry, there have been rapid advances in instrumental design, experimental methods through which the range of potential applications of contemporary IMS techniques have diversified. Having significant research/applied industrial potential and encompasses multi-/cross-disciplinary areas of science, Whilst IMS-Mass spectrometry (IMS-MS) have recently been recognized.